Development and Evaluation of a Monolithic Floating Drug Delivery System for Acyclovir
نویسندگان
چکیده
منابع مشابه
Development and evaluation of a monolithic floating drug delivery system for acyclovir.
Acyclovir (ACV), a model drug for this study, is one of the most effective drugs against viruses of the herpes group. Absorption of orally administered ACV is variable and incomplete, with a bioavailability of ca. 15-30%. The drug is absorbed in the duodenum after oral administration and hence, preparation of a floating drug delivery system (FDDS) for ACV may increase oral absorption of the dru...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2012
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.60.172